Longevity & Healthspan Medicine for Women — Dr. Shamsah Amersi
Longevity & Healthspan Medicine for Women
By Dr. Shamsah Amersi, MD, FACOG
Pioneering the future of women’s medicine through hormones, precision diagnostics, and proactive longevity care.
A New Model of Women’s Health: Proactive, Preventive, and Personal
For over 23 years, I’ve helped women navigate every phase of life—from adolescence, childbirth, PCOS, insulin resistance, perimenopause and beyond. One truth has become clear: women don’t just want to live longer—they want to live better.
Traditional medicine reacts to disease after it happens. My approach is the opposite. I practice proactive longevity medicine, identifying early cellular and hormonal changes and intervening before decline begins. Using advanced biomarker testing, I map the key systems that determine how you age—metabolic, hormonal, vascular, inflammatory, and cognitive—so we can enhance resilience, performance, and longevity from the inside out.
Hormones: The Breakthrough in Women’s Longevity
Hormones are not just about reproduction—they are the biological language that directs metabolism, cognition, bone health, cardiovascular function, and vitality. When they decline, the effects ripple across every system.
As a world-class OB-GYN with decades of clinical experience on tens of thousands of patients, I specialize in bioidentical hormone optimization—a scientifically precise, individualized approach that restores your body’s natural hormonal architecture.
The hormones I prescribe are one of the most powerful breakthroughs in modern women’s medicine—proven to:
- Protect the brain from cognitive decline and dementia
- Strengthen bones and prevent osteoporosis
- Support muscle mass and metabolic health
- Enhance cardiovascular function and lipid balance
- Restore sexual vitality, energy, and confidence
When balanced correctly, hormones act as a longevity engine—helping women think sharper, move stronger, and live longer with vibrancy and grace.
Bioidentical Hormone Therapy: Restoring the Body’s Natural Harmony
Unlike synthetic hormones, bioidentical formulations mirror the body’s own molecular structure. Through advanced blood testing, I identify each patient’s unique hormonal fingerprint—estrogen, progesterone, testosterone, thyroid, cortisol, and DHEA—and rebalance them with exact precision.
This tailored approach:
- Reverses fatigue, brain fog, and sleep disruption
- Improves mood, focus, and emotional stability
- Protects the heart, bones, and blood vessels
- Revives libido and vaginal health
- Reduces hot flashes, night sweats, and weight gain
Restoring hormones under expert supervision is not about turning back the clock—it’s about turning on your body’s ability to regenerate, repair, and thrive.
Targeted Supplementation and Cellular Nutrition
Longevity begins at the cellular level. I use micronutrient and metabolic testing to identify deficiencies that slow energy production, impair detoxification, or accelerate inflammation.
My protocols often include:
- Omega-3s, CoQ10, and NAD⁺ boosters to enhance mitochondrial energy
- Magnesium, zinc, vitamin D, and B-complex vitamins for metabolic balance and hormone synthesis
- Creatine, collagen peptides, and adaptogens to support brain performance, muscle integrity, and stress resilience
Each supplement plan is personalized—designed to nourish your body, repair your cells, and sustain the foundation of youth: energy.
Weight Loss, GLP-1 Therapy, and Visceral Fat Reduction
Weight management after 40 is not simply about diet—it’s about hormone and metabolic recalibration. With aging and estrogen decline, women often develop insulin resistance and accumulate visceral fat, the deep abdominal fat that drives inflammation, heart disease, and cognitive decline.
I address this from multiple angles:
- GLP-1 therapies (such as semaglutide or tirzepatide) to reset appetite regulation, improve insulin sensitivity, and promote sustainable fat loss
- Hormone optimization to restore leptin signaling, thyroid function, and metabolic rhythm
- Nutrition and muscle-building protocols to preserve lean mass and improve body composition
The goal is not just to lose weight—it’s to eliminate visceral fat, rebalance insulin, and restore your body’s natural capacity to burn energy efficiently. This approach reduces cardiovascular and dementia risk, improves longevity markers, and transforms metabolic health from the inside out.
When paired with hormone balance, GLP-1 therapy becomes more than a weight-loss tool—it’s a metabolic reset button for women seeking long-term vitality.
Muscle Mass and Strength Preservation
Muscle is medicine. After midlife, the preservation of lean muscle becomes one of the strongest predictors of longevity. I emphasize resistance training, adequate protein intake, and creatine supplementation, supported by hormonal therapy, to maintain and build muscle mass.
This synergy enhances metabolism, stabilizes blood sugar, prevents falls and fractures, and keeps women strong, agile, and confident through every decade.
Brain Health and Cognitive Longevity
Women are twice as likely as men to develop Alzheimer’s—and hormonal decline is a major driver. Estrogen, testosterone, and DHEA play critical neuroprotective roles, enhancing cerebral blood flow and glucose metabolism.
Through biomarker testing and cognitive screening, I assess risk and build neuroprotective plans that integrate hormone restoration, creatine, omega-3s, and sleep optimization. The result is preserved focus, memory, and creativity—supporting not just brain health, but brain excellence.
Bone and Cardiovascular Protection
Estrogen deficiency accelerates both bone loss and cardiovascular disease. My protocols integrate DEXA scans, vascular testing, and calcium scoring with hormone therapy, vitamin D and K2 optimization, and strength training.
By addressing these systems together, we build the two pillars of female longevity—a strong heart and strong bones—ensuring stability and vitality well into later life.
Sexual Health and Intimacy
Sexual well-being is an essential part of women’s health. I treat low libido, dryness, and discomfort with testosterone and estrogen restoration, vaginal DHEA, PRP, and regenerative therapies, addressing not only physical symptoms but also confidence, intimacy, and feminine vitality.
Reclaiming sexual wellness is often the moment women realize how profoundly hormone balance transforms every aspect of living.
Cancer and Genetic Screening
Longevity medicine requires vigilance. I incorporate comprehensive cancer prevention and hereditary genetic testing (BRCA1/2, Lynch syndrome, CHEK2, and beyond) with tumor and inflammatory markers to detect risks early.
Prevention allows power—transforming anxiety into action and knowledge into safety.
My Philosophy: Living Younger, Longer, and Better
Longevity is not an aesthetic pursuit—it is a science of resilience. The integration of hormonal precision, metabolic optimization, and proactive diagnostics represents the greatest advancement in women’s medicine in decades.
The hormones I prescribe are not about vanity; they are about vitality—restoring brain function, muscle mass, bone density, and joy. When expertly managed, they become one of the most important tools in helping women live longer, live better, and stay fully alive.
As a physician, my mission is to help women not merely survive the transitions of aging—but to rise through them stronger, sharper, and more radiant than ever before.







































